Hormone Optimization

Larger than a grain of rice and smaller than a Tic Tac, BHRT pellets are composed of either estradiol (an estrogen hormone) or testosterone. EvexiPEL® pellets are manufactured by FarmaKeio, a leading compounding pharmacy in the United States, where the hormones are pressed or fused into small, solid cylinders.

During BHRT with pellets, the practitioner makes a tiny incision – usually in the buttocks or flank – then inserts the pellets into the fatty tissue under the skin. The practitioner then closes the incision, without the need for stitches. To prevent patient discomfort, a local anesthetic is applied to the insertion site prior to the procedure.

In response to physical activity or emotional stress (whether it’s good stress or bad), the pellets release estradiol and/or testosterone into the body. Thanks to the pellets, which are securely tucked away beneath the skin, the patient receives a steady stream of hormones, which keeps annoying mood and energy fluctuations at bay.

Is the EvexiPEL® method different than other forms of pellet therapy?

Yes! And the EvexiPEL® formulation has been shown to produce better outcomes for patients, too. After a decade treating thousands of patients, EvexiPEL® founder Terri DeNeui, MSN, APRN-BC worked diligently with a team of experts to develop a proprietary pellet formula.

Put into practice at one of the largest known hormone pellet therapy providers in the country – EVEXIAS® Medical Centers – the formulation yielded the following results:

• Reduced scar tissue, resulting in far fewer pellet extrusions. Decreasing additional office visits dealing with complications and wasting valuable resources in practitioner clinics.
• Far fewer boosts required in new patients. More effective and convenient for patients.
• Quicker Absorption. Patients reported more comprehensive symptom relief sooner than with other compounded pellets.
• More consistent absorption over time. Thus ensuring longer lasting therapeutic results.
• Increased practitioner and patient satisfaction. Period.

Research consistently shows pellet implants offer a superior way to deliver hormones in women and men. Implanted in the fatty tissue under the skin, pellets release a constant stream of hormones into the body, 24/7/365, mimicking the way the body naturally releases hormones.

Convenience is also a key. With pellets, patients undergo the procedure two or three times a year and get on with life. Other modalities, like pills and messy creams, need to be used daily. Patches work a bit better, but the absorption of skin-based delivery methods is variable. People also lose sensitivity over time, which means patients will eventually need to find a new spot to apply the cream or adhere the patch.

Pellet implants typically last 5 to 6 months in men (two visits per year) and 4 to 5 months in women (three visits per year).

A topical anesthetic is applied to the site of the implant, which is placed in the fatty tissue under the skin. Patients experience little to no discomfort during or after the procedure.

Most female patients begin to “feel better” within 48 to 72 hours, though it may take a week or two for some women to notice a difference. Men can expect to experience the benefits of their pellet implants within 1 to 2 weeks. To achieve optimal health, living a healthy lifestyle – balanced diet and regular exercise – goes hand-in-hand with hormone balance.

While most people experience substantial benefits after the first round of therapy, many patients experience more pronounced benefits after the second round of pellet implants. Therefore, patients should expect to have the procedure performed at least twice before experiencing optimum results. People don’t get out of balance overnight, so it often takes a few months to get back on track.